It is estimated that almost 21 million Americans have diabetes. This represents 7% of the entire population. Almost everyone knows someone that has diabetes. Diabetes is disorder of metabolism. Metabolism is the process by which our bodies use food for growth and energy. Most of the food we eat is broken down into a form of sugar called glucose. Glucose is the main fuel source for the body. Glucose is formed as our food is digested. Glucose then enters the bloodstream where it is used by cells for energy. For glucose to enter into cells, the hormone insulin must be present. Insulin is produced by the pancreas, a large gland located behind the stomach. When we eat, glucose rises in the bloodstream causing the pancreas to secrete insulin which allows glucose to move from the bloodstream into cells.

In diabetes, however, the pancreas either does not produce enough insulin or cells do not respond appropriately to insulin and glucose does not enter the cells. Glucose builds up in the blood and passes out of the body in urine. The body loses its main source of fuel even though the blood contains large amounts of glucose.

The most common type of diabetes is type 2 diabetes. Over 90% of people with diabetes have type 2 diabetes. When type 2 diabetes is diagnosed, the pancreas is usually still making enough insulin. For unknown reasons the body cannot use the insulin properly. This is known as insulin resistance. Over time, insulin production decreases which leads to worsening diabetes.

Chromium is a trace mineral used by the human body for normal carbohydrate and fat metabolism. Low blood levels of chromium have been associated with decreased insulin sensitivity. It is thought that chronically low levels of chromium may contribute to insulin resistance. Biotin is a member of the B-vitamin family. It is necessary for both metabolism and growth in humans. It is important in the production of fatty acids, antibodies, and digestive enzymes. Biotin increases insulin production and enhances the uptake of glucose by muscle cells.

Recent studies have demonstrated positive effects of chromium picolinate and biotin on blood glucose levels, insulin sensitivity and fat metabolism. Response within 30 days of supplementing these nutrients in combination has been demonstrated in fasting blood glucose levels. Use of them for 90 days or more has been shown to reduce A1c levels. A1c is used to monitor 90-day fasting blood glucose control. Supplementation with 600 mcg of chromium picolinate and 2 mg of biotin taken in the morning may help to improve blood glucose control. These nutrients can be taken safely as part of lifestyle modifications considered first-line therapy for diabetes.

References: http://diabetes.niddk.nih.gov/dm/pubs/overview/index.htm, http://www.uspharmacist.com/index.asp?show=article&page=8_1895.htm.

[Return to Archive Index]

[PageTop]